Coming soon
Environmental Toxicology
This course will enable the students to -
- Provide an insight into environmental toxicology, including the major classes of toxicants in the environment, their fate in the environment, their disposition in organisms, and their biochemical mechanisms of toxicity.
- Assemble knowledge of environmental toxicology for conducting applied research for the betterment of the human race.
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Course |
Course Outcomes |
Learning and teaching strategies |
Assessment Strategies |
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Course Code |
Course Title |
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24ENV 322 |
Environmental Toxicology |
CO74: Develop knowledge about the various toxicants their movement and chemical conversion in the ecosystem CO75: Examine the sources of toxicants in the environment and their life cycle CO76: Interrelate the chemical mechanism of toxicants with different systems of the human body CO77: Examine the chemical processes occurring and the fate of toxicants in the human body CO78: Design monitoring programmes for a wide range of Environmental toxicants. CO79: Contribute effectively in course-specific interaction |
Approach in teaching: Interactive Lectures, Group Discussions, Use of informative videos Learning activities for the students: Discussion of case studies, PowerPoint presentations, Brainstorming, Weekly class assessment |
PowerPoint presentations, Assignments, Class tests, Semester end examinations |
- Introduction to Environmental and Ecotoxicology
- Definition of Toxicology
- Branches of Toxicology
- Scope and Importance of Toxicology
- Goals of toxicology
- Dose of Toxicants
- Effect and Response (Acute effects, Chronic effects, Reversible and Irreversible effects and Local and Systemic effects)
- Dose-Response Relationship (Graded and Quantal Response)
- Time action curves
- Toxicants and toxicity
- Factors that affect the environmental concentration of toxicants
- Toxicology of Pesticides – (Types; Effects on Human Health).
- Toxicology of Heavy Metals - Arsenic, Cadmium, Lead and Mercury- (Sources and Emissions and Harmful Effects on Human Health)
- Toxicology of Radioactive Substances – (Types and Biological Effects on animals – Somatic and Genetic effects).
- Basic concept of Translocation
- Absorption
- Biotransformation (Phase I and Phase II reactions)
- Excretion of Xenobiotics
- Definition of Biomagnification and Biomonitoring
- Biomagnification of:
- Pesticides
- Metals
- Radioactive substances
- Objectives of Biomonitoring
- Bioindicators and Environmental Monitoring
- Bioassay and its Applications in Toxicology
ESSENTIAL READING
- Casarett, & Doull’s. (2008). Toxicology: The Basic Science Of Poisons (7th Ed.). New York: McGraw-Hill.
- Sharma, P. (2005). Environmental Biology And Toxicology. Meerut: Rastogi Publication.
- Shaw, I., & Chadwick, J. ( 1998). Principles Of Environmental Toxicology. Taylor & Francis Ltd.Wright, D. A., & Welbourn, P. (2002). Environmental Toxicology. New York: Cambridge University Press.
- Hodgson, E. (2010). A Textbook Of Modern Toxicology. A John Wiley & Sons, Inc.
- Pandey, K., Shukla, J. P., & Trivedi, S. P. (2011). Fundamentals Of Toxicology. New Central Book Agency.
SUGGESTED READING
- Helferich, W., & Winter, C. K. (2001). Food Toxicology. CRC Press.
- Hughes, W.W(1196)ESSENTIALS OF ENVIRONMENTAL TOXICOLOGY: The Effects of Environmentally Hazardous Substances on Human Health.Taylor & Francis.
- Roberts, S.M., James, R.C. and. Williams, P.L(2015) Principles of Toxicology Environmental and Industrial Applications. Wiley publications
e-RESOURCES
o Basics of Toxicology
http://www.eolss.net/sample-chapters/c09/e4-12.pdf
o Introduction to toxicology https://ec.europa.eu/health/ph_projects/2003/action3/docs/2003_3_09_a21_en.pdf
o Branches of toxicology
https://www.atsdr.cdc.gov/training/toxmanual/modules/1/lecturenotes.html
o Absorption of toxicants
https://nature.berkeley.edu/~dnomura/pdf/Lecture2AbsorptionDistribution.pdf
o Biomonitoring of Pollutants
http://www.nbrienvis.nic.in/Database/1_2019.aspx
o Toxicity of pesticides
https://edis.ifas.ufl.edu/pdf/PI/PI00800.pdf
JOURNALS
- Journal of toxicology and health
- Journal of Applied Toxicology
- Toxicology research
