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ENVIRONMENTAL TOXICOLOGY
Paper Code:
ENV 322
Credits:
5
Contact Hours:
75.00
Max. Marks:
100.00
12.00
Unit I:
Fundamentals of Ecotoxicology
- Introduction to Toxicology
- Definition of Toxicology
- Principle Divisions and Branches of Toxicology
- Scope And Importance of Toxicology
- Goals of toxicology
16.00
Unit II:
Dose and Toxicity
- Dose of Toxicants
- Effect and Response –(Acute effects, Chronic effects, Reversible and Irreversible effects and Local and Systemic effects)
- Dose Response Relationship – (Graded and Quantal Response)
- Time action curves
- Toxicity curves
- Toxicants and toxicity
- Factors that affect environmental concentration of toxicants
- Factors influencing toxicity
16.00
Unit III:
Toxicants of Public Health Hazards
- Toxicology of Pesticides – (Types; Effects on Human Health).
- Toxicology of Heavy Metals - Arsenic, Cadmium, Lead and Mercury- (Sources and Emissions and Harmful effects on Human Health)
- Toxicology of Radioactive Substances – (Types and Biological Effects on animals – Somatic and Genetic effects).
15.00
Unit IV:
Translocation of Xenobiotics
- Basic concept of Translocation
- Absorption
- Biotransformation (Phase I and Phase II reactions)
- Excretion of Xenobiotics
16.00
Unit V:
Biomagnification and Biomonitoring of Toxic Chemicals
- Definition of Biomagnification and Biomonitoring
- Biomagnification of
- pesticides
- metals
- radioactive substances
- Objectives of Biomonitoring
- Bioindicators and Environmental monitoring
- Bioassay and its applications in Toxicology
Essential Readings:
- Casarett, & Doull’s. (2008). Toxicology: The Basic Science Of Poisons (7th Ed.). New York: Mcgraw-Hill.
- Helferich, W., & Winter, C. K. (2001). Food Toxicology. Crc Press.
- Hodgson, E. (2010). A Textbook Of Modern Toxicology. A John Wiley & Sons, Inc.
- Pandey, K., Shukla, J. P., & Trivedi, S. P. (2011). Fundamentals Of Toxicology. New Central Book Agency.
- Sharma, P. (2005). Environmental Biology And Toxicology. Meerut: Rastogi Publication.
- Shaw, I., & Chadwick, J. ( 1998). Prinicples Of Environmental Toxicology. Taylor & Francis Ltd.
- Wright, D. A., & Welbourn, P. (2002). Environmental Toxicology. New York: Cambridge University Press.
Academic Year:
