ENVIRONMENTAL TOXICOLOGY

Paper Code: 
ENV 322
Credits: 
5
Contact Hours: 
75.00
Max. Marks: 
100.00
12.00
Unit I: 
Fundamentals of Ecotoxicology
  • Introduction to Toxicology
  • Definition of Toxicology
  • Principle Divisions and Branches of Toxicology
  • Scope And Importance of Toxicology
  • Goals of toxicology
16.00
Unit II: 
Dose and Toxicity
  • Dose of Toxicants
  • Effect and Response –(Acute effects, Chronic effects, Reversible and Irreversible effects and Local and Systemic effects)
  • Dose Response Relationship – (Graded and Quantal Response)
  • Time action curves
  • Toxicity curves
  • Toxicants and toxicity
  • Factors that affect environmental concentration of toxicants
  • Factors influencing toxicity
16.00
Unit III: 
Toxicants of Public Health Hazards
  • Toxicology of Pesticides – (Types; Effects on Human Health).
  • Toxicology of Heavy Metals - Arsenic, Cadmium, Lead and Mercury- (Sources and Emissions and Harmful effects on Human Health)
  • Toxicology of Radioactive Substances – (Types and Biological Effects on animals – Somatic and Genetic effects).

 

15.00
Unit IV: 
Translocation of Xenobiotics
  • Basic concept of Translocation
  • Absorption
  • Biotransformation (Phase I and Phase II reactions)
  • Excretion of Xenobiotics.

 

16.00
Unit V: 
Biomagnification and Biomonitoring of Toxic Chemicals
  • Definition of Biomagnification and Biomonitoring
  •  Biomagnification of
  • Pesticides
  • Metals
  • Radioactive substances       
  • Objectives of Biomonitoring
  •  Bioindicators and Environmental monitoring
  •  Bioassay and its applications in Toxicology

 

Essential Readings: 
  • ·         Casarett, & Doull’s. (2008). Toxicology: The Basic Science Of Poisons (7th Ed.). New York: Mcgraw-Hill.
  • ·         Helferich, W., & Winter, C. K. (2001). Food Toxicology. Crc Press.
  • ·         Hodgson, E. (2010). A Textbook Of Modern Toxicology. A John Wiley & Sons, Inc.
  • ·         Pandey, K., Shukla, J. P., & Trivedi, S. P. (2011). Fundamentals Of Toxicology. New Central Book Agency.
  • ·         Sharma, P. (2005). Environmental Biology And Toxicology. Meerut: Rastogi Publication.
  • ·         Shaw, I., & Chadwick, J. ( 1998). Prinicples Of Environmental Toxicology. Taylor & Francis Ltd.
  • ·         Wright, D. A., & Welbourn, P. (2002). Environmental Toxicology. New York: Cambridge University Press.
Academic Year: 
2017-2018
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