ENVIRONMENTAL TOXICOLOGY

Paper Code: 
ENV 322
Credits: 
5
Contact Hours: 
75.00
Max. Marks: 
100.00
Objective: 

Course objectives

This course will enable the students to -

  1. Get an insight of environmental toxicology, including the major classes of toxicants in the environment, their fate in the environment, their disposition in organisms, and their biochemical mechanisms of toxicity.
  2. Gain knowledge of environmental toxicology for conducting applied research for betterment of human race

 

Course Outcomes (COs):

Course

Learning outcomes

(at course level)

Learning and teaching strategies

Assessment

Strategies

Paper Code

Paper Title

ENV 322

Environmental Toxicology

Upon completion of this course, student will be able to:

CO53:  Develop knowledge about the various toxicants, their movement and chemical conversion in the ecosystem

CO54: Identify the sources of toxicants in the environment

CO55:Interrelate the chemical mechanism of  toxicants  with different systems of the human body

CO56:  Design monitoring programmes for a wide range of Environmental toxicants

Approach in teaching:

Interactive Lectures, Group Discussions, Use of informative videos

Learning activities for the students:

Discussion of case studies, Power point presentations, Brain storming, Weekly class assessment

Power point presentations, Assignments, Class test,  Semester end examinations

 

 

 

 

12.00
Unit I: 
Fundamentals of Ecotoxicology
  • Introduction to Environmental and Ecotoxicology
  • Definition of Toxicology
  • Principle Divisions and Branches of Toxicology
  • Scope And Importance of Toxicology
  • Goals of toxicology
16.00
Unit II: 
Dose and Toxicity
  • Dose of Toxicants
  • Effect and Response –(Acute effects, Chronic effects, Reversible and Irreversible effects and Local and Systemic effects)
  • Dose Response Relationship – (Graded and Quantal Response)
  • Time action curves
  • Toxicity curves
  • Toxicants and toxicity
  • Factors that affect environmental concentration of toxicants
  • Factors influencing toxicity
16.00
Unit III: 
Toxicants of Public Health Hazards
  • Toxicology of Pesticides – (Types; Effects on Human Health).
  • Toxicology of Heavy Metals - Arsenic, Cadmium, Lead and Mercury- (Sources and Emissions and Harmful effects on Human Health)
  • Toxicology of Radioactive Substances – (Types and Biological Effects on animals – Somatic and Genetic effects)
15.00
Unit IV: 
Translocation of Xenobiotics
  • Basic concept of Translocation
  • Absorption
  • Biotransformation (Phase I and Phase II reactions)
  • Excretion of Xenobiotics
16.00
Unit V: 
Biomagnification and Biomonitoring of Toxic Chemicals
  • Definition of Biomagnification and Biomonitoring
  •  Biomagnification of
    • pesticides
    • metals
    • radioactive substances       
  • Objectives of Biomonitoring
  •  Bioindicators and Environmental monitoring
  •  Bioassay and its applications in Toxicology

 

Essential Readings: 
  • ·         Casarett, & Doull’s. (2008). Toxicology: The Basic Science Of Poisons (7th Ed.). New York: Mcgraw-Hill.
  • ·         Helferich, W., & Winter, C. K. (2001). Food Toxicology. Crc Press.
  • ·         Hodgson, E. (2010). A Textbook Of Modern Toxicology. A John Wiley & Sons, Inc.
  • ·         Pandey, K., Shukla, J. P., & Trivedi, S. P. (2011). Fundamentals Of Toxicology. New Central Book Agency.
  • ·         Sharma, P. (2005). Environmental Biology And Toxicology. Meerut: Rastogi Publication.
  • ·         Shaw, I., & Chadwick, J. ( 1998). Prinicples Of Environmental Toxicology. Taylor & Francis Ltd.
  • ·         Wright, D. A., & Welbourn, P. (2002). Environmental Toxicology. New York: Cambridge University Press.
Academic Year: 
2019-2020
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