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Environmental Toxicology [1]

Paper Code: 
ENV 322
Credits: 
5
Contact Hours: 
75.00
Max. Marks: 
100.00
Objective: 

This course will enable the students to -

  1. Provide an insight of environmental toxicology, including the major classes of toxicants in the environment, their fate in the environment, their disposition in organisms, and their biochemical mechanisms of toxicity.
  2. Assemble knowledge of environmental toxicology for conducting applied research for betterment of human race

Course Outcomes (COs):

Course

Learning outcomes

(at course level)

Learning and teaching strategies

Assessment

Strategies

Paper Code

Paper Title

ENV 322

Environmental Toxicology

Upon completion of this course, student will

CO79:  Develop knowledge about the various toxicants, their movement and chemical conversion in the ecosystem

CO80: Examine the sources of toxicants in the environment and their life cycle

CO81:  Design monitoring programmes for a wide range of Environmental toxicants

CO82: Interrelate the chemical mechanism of  toxicants  with different systems of the human body

CO83: Formulate methods for removal of toxicants from the environmental components using latest technologies

CO84: Investigate the harmful effects of chemicals at different levels of the ecosystem and design develop new methods for quantification of toxicants

 

Approach in teaching:

Interactive Lectures, Group Discussions, Use of informative videos

Learning activities for the students:

Discussion of case studies, Power point presentations, Brain storming, Weekly class assessment

Power point presentations, Assignments, Class test,  Semester end examinations

 

 

 

 

12.00
Unit I: 
Fundamentals of Ecotoxicology
  • Introduction to Environmental and Ecotoxicology
  • Definition of Toxicology
  • Principle Divisions and Branches of Toxicology
  • Scope And Importance of Toxicology
  • Goals of toxicology
16.00
Unit II: 
Dose and Toxicity
  • Dose of Toxicants
  • Effect and Response – (Acute effects, Chronic effects, Reversible and Irreversible effects and Local and Systemic effects)
  • Dose Response Relationship – (Graded and Quantal Response)
  • Time action curves
  • Toxicants and toxicity
  • Factors that affect environmental concentration of toxicants
  • Factors influencing toxicity
16.00
Unit III: 
Toxicants of Public Health Hazards
  • Toxicology of Pesticides – (Types; Effects on Human Health).
  • Toxicology of Heavy Metals - Arsenic, Cadmium, Lead and Mercury- (Sources and Emissions and Harmful effects on Human Health)
  • Toxicology of Radioactive Substances – (Types and Biological Effects on animals – Somatic and Genetic effects).

 

15.00
Unit IV: 
Translocation of Xenobiotics
  • Basic concept of Translocation
  • Absorption
  • Biotransformation (Phase I and Phase II reactions)
  • Excretion of Xenobiotics

 

16.00
Unit V: 
Biomagnification and Biomonitoring of Toxic Chemicals
  • Definition of Biomagnification and Biomonitoring
  • Biomagnification of:
    • Pesticides
    • Metals
    • Radioactive substances       
  • Objectives of Biomonitoring
  • Bioindicators and Environmental monitoring
  •  Bioassay and its applications in Toxicology

 

Essential Readings: 

ESSENTIAL READING

  • Casarett, & Doull’s. (2008). Toxicology: The Basic Science Of Poisons (7th Ed.). New York: Mcgraw-Hill.
  • Sharma, P. (2005). Environmental Biology And Toxicology. Meerut: Rastogi Publication.
  • Shaw, I., & Chadwick, J. ( 1998). Prinicples Of Environmental Toxicology. Taylor & Francis Ltd. Wright, D. A., & Welbourn, P. (2002). Environmental Toxicology. New York: Cambridge University Press.
  • Hodgson, E. (2010). A Textbook Of Modern Toxicology. A John Wiley & Sons, Inc.
  • Pandey, K., Shukla, J. P., & Trivedi, S. P. (2011). Fundamentals Of Toxicology. New Central Book Agency.

SUGGESTED READING

  • Helferich, W., & Winter, C. K. (2001). Food Toxicology. Crc Press.
  • Hughes, W.W(1196)ESSENTIALS OF ENVIRONMENTAL TOXICOLOGY: The Effects of Environmentally Hazardous Substances on Human Health .Taylor & Francis.
  • Roberts, S.M., James,R.C. and. Williams,P.L(2015) Principles of Toxicology Environmental and Industrial Applications. Wiley publications

 

References: 

e-RESOURCES

JOURNALS

  • Journal of toxicology and health
  • Journal of Applied toxicology
  • Toxicology research

 

Academic Year: 
2022-2023 [8]

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Source URL: https://environment.iisuniv.ac.in/courses/subjects/environmental-toxicology-18

Links:
[1] https://environment.iisuniv.ac.in/courses/subjects/environmental-toxicology-18
[2] http://www.eolss.net/sample-chapters/c09/e4-12.pdf
[3] https://ec.europa.eu/health/ph_projects/2003/action3/docs/2003_3_09_a21_en.pdf
[4] https://www.atsdr.cdc.gov/training/toxmanual/modules/1/lecturenotes.html
[5] https://nature.berkeley.edu/~dnomura/pdf/Lecture2AbsorptionDistribution.pdf
[6] http://www.nbrienvis.nic.in/Database/1_2019.aspx
[7] https://edis.ifas.ufl.edu/pdf/PI/PI00800.pdf
[8] https://environment.iisuniv.ac.in/academic-year/2022-2023