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ENVIRONMENTAL TOXICOLOGY [1]

Paper Code: 
ENV 501
10.00
Unit I: 
Introduction, Scope and Importance of Toxicology
  • Definition
  • Principle Divisions and Branches
  • Scope and importance

 

10.00
Unit II: 
Basic concept of Toxicology
  • Dose of Toxicants
  • Effect and response –(acute effects, chronic effects, reversible and irreversible effects and local and systemic effects)
  • Dose response relationship – (graded and quantal response)
  • Absorption, Distribution and Excretion (Basic concept)
  • Bioaccumulation of Xenobiotics
9.00
Unit III: 
Transport and Fate of Toxicants in the Environment
  • Sources of Toxicants to the Environment
  • Transport Processes
    • Advection
    • Diffusion
  • Transformation Processes
    • Reversible Reactions (Ionization, Precipitation and Dissolution, Complexation and Chemical Speciation)
    • Irreversible Reactions (Hydrolysis, Photolysis, Oxidation-Reduction reactions, Biotransformations)

 

Unit IV: 
Toxicity of Metals
  • Sources and toxic effects on humans of
    • Arsenic
    • Lead
    • Cadmium
    • Mercury
  • Toxicity of Pesticides: Organochlorines and Organophosphates

 

8.00
Unit V: 
Food Additives and Contaminants
  • Incidental or indirect additives
  • Intentional or direct additives
    • Antioxidants
    • Emulsifiers
    • Flavouring Agents
    • Colour and preservatives
  • Food Toxins
    • Microbial toxins-algal, fungal and bacterial toxins
    • Plant toxins

 

Essential Readings: 
  • ·         Casarett, & Doull’s. (2008). Toxicology: The Basic Science Of Poisons (7th Ed.). New York: Mcgraw-Hill.
  • ·         Helferich, W., & Winter, C. K. (2001). Food Toxicology. Crc Press.
  • ·         Hodgson, E. (2010). A Textbook Of Modern Toxicology. A John Wiley & Sons, Inc.
  • ·         Pandey, K., Shukla, J. P., & Trivedi, S. P. (2011). Fundamentals Of Toxicology. New Central Book Agency.
  • ·         Sharma, P. (2005). Environmental Biology And Toxicology. Meerut: Rastogi Publication.
  • ·         Shaw, I., & Chadwick, J. ( 1998). Prinicples Of Environmental Toxicology. Taylor & Francis Ltd.
  • ·         Wright, D. A., & Welbourn, P. (2002). Environmental Toxicology. New York: Cambridge University Press.
Academic Year: 
2017-2018 [2]

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[1] https://environment.iisuniv.ac.in/courses/subjects/environmental-toxicology-3
[2] https://environment.iisuniv.ac.in/academic-year/2017-2018